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These results indicate full integration of BUD13 into the activated spliceosome

Phase II typically funds up to $1,000,000 to $1,500,000 for 24-36 months to continue the R&D effort from the completed Phase I project and work towards a prototype demonstration

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Cytosolic Ca 2+ entering the mitochondrial matrix through the mitochondrial Ca 2+ uniporter (MCU) stimulates OXPHOS by activating pyruvate dehydrogenase phosphatase, which in turn, increases the activity of pyruvate dehydrogenase complex [21]