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It is well known that activity of cytosolic enzymes in blood plasma is increased as a result of exhaustive exercise

The data that support the findings of this study are available from the corresponding author, NB, upon reasonable request

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Artesunate Studies (114, 115) have found that the antimalarial drug artemisinin analog artesunate (ARS) has strong immunosuppressive activity in RA model, which can inhibit the formation of germinal centers, B cell proliferation and the production of autoantibodies, increase Foxp3 expression, reduce the formation of pannus, and cartilage and bone erosion