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Although this finding was consistent with the perspective that cell-autonomous HIF1a in Tbr2 + INPs caused oxidative stress among neural progenitors, HIF1a is also normally present in multiple cell types throughout the SGZ where it acts as a pro-neurogenesis signal among early neuroprogenitors 48,61

Glucose homeostasis was assessed through an IPGTT with 2.5 g/kg glucose

What we tell patients: Keep training, but dont try to PR every session Reduce intensity on the affected area for the first 2 to 3 weeks Add mobility work, not subtract it Listen to pain signals