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Blood-brain barrier breakdown and neovascularization processes after stroke and traumatic brain injury

We studied the activity of system x c and GSH content in human ovarian cancer cell line (A2780) and its cisplatin (CDDP)-resistant variant (A2780DDP)

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Although the SVCT are the primary transporters for ascorbate, cells are also capable of ascorbate uptake via the activity of the facilitative glucose transporters, GLUT1, GLUT3, and GLUT4