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574 TetRs, however, play a far more widespread regulatory role in metabolism, controlling the expression of genes involved in central carbon metabolism, antibiotic production, quorum sensing, and many other aspects of prokaryotic physiology

Scientists have studied how certain isolated peptides might support or influence these processes in targeted ways

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678,758 Interestingly, some FolEIB enzymes are reported to be active with Mg II , to an extent on par with that of Co II , which is puzzling given the presence of clearly softer ligands in both FolEIB coordination shells