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The concentrations (1.6, 6.4, or 25.6 mM) of L-carnitine were selected based on the physiological concentration in human skeletal muscle (approximately 4.5 mM) (Evans and Fornasini, 2003) and a preliminary experiment indicating non-cytotoxicity at up to 25.6 mM (Figure 4)

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Three patients with -glutamyl transpeptidase deficiency have been studied and found to have a complete deficiency of leukotriene D4 biosynthetsis [38]