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May aid in healing of intestinal anastomoses and fistulas, and shows benefits in models of inflammatory bowel disease, Crohns disease, and ulcerative colitis235

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In this phase, one or more of the body systems has weakened to such a point that a pathological clinical state of the affected system surfaces

The EC50 values obtained fitting the ELISA values revealed that the apparent binding affinity of the PV2-PV3 fusion protein was 61.1 nM, while that of PV2-S71 + PV3-N77 was 6.1 nM, representing a 10-fold improvement in binding affinity for BsNb-ncAA compared to BsNb-fusion (Fig