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Yet, pramlintide has a short half-life (20-45 min) and therefore must be injected subcutaneously 3 times daily before meals

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doi: 10.1038/ijo.2012.48 237 DavidLAMauriceCFCarmodyRNGootenbergDBButtonJEWolfeBEet al

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Cheng FS, Lei JX, Zhang J et al (2025) Global burden of Alzheimer disease and other dementias reveals escalating geographical disparities and metabolic risks: a comprehensive analysis of 1990-2021 data