If they are not, the result may be: cloudiness flakes precipitation or aggregation That incompatibility can be triggered by: pH mismatch benzyl alcohol altering solubility residual salts interacting with the solvent the sudden transition from dry to liquid Once that happens, molecules that would normally remain separate begin to cluster
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NAD+ is the most cited example: it is a comparatively high-volume, sometimes uncomfortable injection that some research protocols describe delivering IM (or slow SubQ) rather than as a fast SubQ bolus
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