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Importantly, either genetic silencing of NCOA4 or treatment with the iron chelator deferoxamine (DFO) significantly attenuated these pathological changes, resulting in over 60% improvement in neuronal survival (Plascencia-Villa and Perry, 2021)

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2007 Jul 27;282(30):21889900

10.1371/journal.pone.0130177 PLoS One 44 CollinsJ

Results: Leukocyte infiltration peaked early with neutrophils and macrophages, followed by sustained increases in T lymphocytes (CD4+ and CD8+) from day 15 to day 30