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doi: 10.1097/00041444-200109000-00003 66 AlbrightFLightKLightABatemanLCannon-AlbrightLA

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Weight-based dosing is not standard for tirzepatide, but the gender-adjusted protocol above represents an attempt to account for body size differences

92 SnyderE

In summary, efforts to uncover disease-modifying treatments in SCA3 should have a robust mechanistic background and, more importantly, sufficient preclinical data to support their reliability and efficacy prior to a potential clinical trial