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Acetaminophen, in particular, is known to produce a toxic metabolite that is normally detoxified by glutathione

Future research should address the discrepancy between the doses administered in animal studies and the corresponding dose levels in humans

In vitro BP incorporation was performed at 37 C for 1 h, and then, the samples were diluted with sample loading buffer (60 mM Tris-Cl (pH 6.8), 10% glycerol, 2% SDS, 1% -mercaptoethanol (ME), 0.01% bromophenol blue) and boiled at 100 C for 10 min

In homozygous human FcRn Tg32 mice, groups of female and male mice (816 weeks, 21.530.0 g, 5 mice/23 cages/group) were given either IV or SC injection, into the scruff of the neck, of 4 mg/kg of GLP-1 albumin fusions, diluted in DPBS (pH 7.4) (Sigma-Aldrich), respectively