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Fortunately, the utilization of exogenous controlled ICD immunotherapies mediated by functional nanomaterials, such as Fe-based nanoparticles inducing magnetothermal therapy (MTT) and photothermal therapies (PTT), has partially mitigated the drawbacks associated with small molecule ICD inducers 14,15

Kumbhar et al., 2022

This effect was likely due to attenuation of spinogenesis promoted by HGF and Dihexa treatments since, without the antagonizing effect of Hinge, each agonist increased mini-AMPA frequencies (Figure 13 A-B and Figure 10) thus forming functional synaptic connections

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