FOXO4-DRI works by disrupting a specific protein interaction (between FOXO4 and p53), which allows these unhealthy cells to undergo natural cell death (apoptosis) without harming healthy cells
Data from participants who received the same injection dose (the saline injection group and the 1 10 7 DPSCs per tooth injection group) across both trials were pooled for analysis, and baseline characteristics for these combined participants were verified (Supplementary Table 13)
Outcome measures include neurological severity scoring, rotarod and beam walk performance, histological assessment of lesion volume, and immunohistochemistry for axonal markers and myelin basic protein
Life Sciences 51(13):1049-1056. [doi.org]
Mind Lab Pro Human Studies Study #1: Information Processing and Reaction Time In a double-blind, placebo-controlled study from the University of Leeds, 105 healthy adults took Mind Lab Pro or placebo for 30 days and completed tests measuring simple reaction time, choice reaction time, and anticipatory timing
