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Several inherent factors within tumor cells and the surrounding tumor microenvironment in the body contribute to chemoresistance, as dose suboptimal chemotherapy dosing (Abdullah 2013

Consistently, DMF significantly induced the expression of antioxidant proteins such as Nqo1 and Gpx4, which are critical for detoxification reaction and GSH utilization (Fig

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BMC Plant Biol 10:119 Wu Y, Zhang D, Chu JY, Boyle P, Wang Y, Brindle ID, De Luca V, Desprs C (2012) The Arabidopsis NPR1 protein is a receptor for the plant defence hormone salicylic acid