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Description

One notable transcription factor activated by mTOR is Myc, which upregulates the expression of enzymes crucial for aerobic glycolysis and other anabolic metabolic routes

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The use of IDH2 inhibitors can reduce 2-HG production, restore T cell metabolic balance, and enhance T cell effector function and persistence [69, 76]

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No therapeutic, diagnostic, or dosing claims are made

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