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This regulatory mechanism contributes to diverse biological processesincluding lipid synthesis, immune modulation, and cell proliferationand plays a critical role in the pathogenesis of coronary artery disease, autoimmune disorders, Antley-Bixler syndrome, and cancer [32,33,34,35]

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Barrier dysfunction due to unavoidable injuries or allergic responses enhances the release of IL-1, leading to the increased formation of cytokine proteins [183, 184]