doi:10.1016/j.bmcl.2018.07.009
What they found: In normal obese mice: AOD-9604 reduced body fat by 21 % vs placebo, hGH by 24 % The AOD-9604 effect was fully dependent on the 3-adrenergic receptor , in knock-out mice no effect The hGH effect was partly independent of 3-AR , in knock-out mice there was still ~10 % fat reduction AOD-9604 did not raise IGF-1 (control level), whereas hGH raised IGF-1 by 80 % No changes in growth, organ weights (except adipose tissue), fasting insulin Why it matters: The study provided the mechanistic basis for AOD-9604 and confirmed the key business hypothesis: it is possible to separate the lipolytic effect of GH from its growth effect
Weight loss, when treated well, becomes less strenuous and easier to attain
Moreover, when you use either of the vitamins with semaglutide, you get the following two hard-to-miss benefits: Enhanced Metabolism and Energy Levels Vitamin B6 : Breaks down proteins and fats efficiently, complements semaglutides appetite-suppressing effects, and reduces nausea
This includes awareness of potential side effects, understanding contraindications, and taking special precautions based on individual health conditions
