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Persons eligible for HCC surveillance Patients with cirrhosis from any cause who would be a candidate for therapy Patients with decompensated cirrhosis and end-stage liver dis ease only if they are eligible for liver transplant Other persons eligible for HCC surveillance are those who have chronic hepatitis B without cirrhosis If African born, begin surveillance at age 20 years If Asian-born male, begin surveillance at age 40 years If Asian-born female, begin surveillance at age 50 years Patient with high HBV DNA level Patient with family history of HCC Patient with active inflammation and increased alanine aminotransferase level Figure 25.7

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HCV-induced oxidative stress by inhibition of Nrf2 triggers autophagy and favors release of viral particles

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