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The 200 to 500mcg figures widely used across clinic and community contexts are derived from animal extrapolation and accumulated self-experimentation, not controlled human trials

(More on this below in the Parkinsons section.) There are a couple of differences in the tissue distribution of the MAOs

As this formulation is supplementing the vitamin b12, so cyanocobalamin (synthetic form of vitamin b12) or hydroxocobalamin is used as active ingredient

Targeting M2phenotypic TAMs reduces the polarization of macrophages toward the M2 phenotype and raises the amount of M1-TAMs, which in turn strengthens the anti-tumor immune microenvironment (38)

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