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Ahn SH, Khalaj K, Young SL, Lessey BA, Koti M, Tayade C

Metabolic modulators Metabolic modulators such as 2-deoxy-D-glucose (2-DG), which acts as an inhibitor of glycolysis, have been shown to reduce the expression of terminal exhaustion markers such as Tim-3 and LAG-3 in T cells while increasing T cell persistence, suggesting that the strategy of short-term inhibition of glycolysis preserves T cell exhaustion without compromising their effector functions and shows promise as a potential metabolic intervention strategy to maintain the antitumor activity of T cells [25]

18, pp1986-1993 [online] Available at: (accessed 4 th April 2022) Vasquez-Lorente, H., Herrera-Quintana, L., Molina-Lopez, J., Gamarra, Y and Planells, E

There are two types of Gu syndrome: brain Gu, which involves brain fog, mood, and cognitive changes