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In the present study, we aimed to look at the association and clinical significance of CMB in patients with APS

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Among the 14 identified candidates, acetylcarnitine was finally selected by confirming whether it was endogenous in the blood, matched with the mass value, and exhibited a significant difference in intensity between the MDD and control groups (Figure 4)

As expected, the induction of primitive streak and intermediate mesoderm was initiated by treatment with CHIR99021 (a Wnt agonist) and Noggin (a BMP inhibitor), the former essential for mesoderm lineage specification and the latter represses lateral plate mesoderm differentiation [11]