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It appears that once steatosis is established, further NAFLD/NASH progression does not promote additional alterations in diacylglyceride-linked lipid metabolism, rendering diacylglycerides to exert an adverse effect already during the early stages of NAFLD development

1d) and remarkably recovered the growth defects of shGDH1 or R162-treated cells (Extended Data Fig

Indeed, the levels of OVA-specific IgE were significantly increased in AIN93G-fed diseased mice, but not in 0.00112% LBI-fed diseased mice, compared to the control mice (Fig

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Rod-shaped microglia represent a morphologically distinct subpopulation of disease-associated microglia