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In this design, group G2 evaluated the effect of exogenous migrasomes alone, whereas group G5 served as a mechanistic rescue experiment, in which exogenous migrasomes were used to recreate a migrasome-rich tumor microenvironment after MOF-919@CCM(+) treatment and to test whether restoring migrasomes could attenuate its antitumor and immunostimulatory effects

Multifunctional chitosan coated poly(lactic-co-glycolic acid) nanoparticles for spatiotemporally controlled codelivery of ceramide and C-phycocyanin to treat atopic dermatitis