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The evidence shows no meaningful benefit for healthy people with normal B12
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They actually perform a pretty complex process that can either work smoothly or get overwhelmed, depending on timing, dosage, and how well your kidneys are functioning overall
The increased risk for these populations is due to low levels of consumption and difficulty with vitamin absorption
This means that AOD-9604: Does not raise IGF-1 , no systemic anabolic effect Does not cause insulin resistance , a frequent side effect of high doses of hGH Has no growth effect , no influence on the growth of bones, soft tissues, organs Does not cause acromegaly , because it does not act as GH It is one of the few molecules where we have managed to surgically separate one effect of GH (lipolysis) from the others
In summary, the implication of IGF-1 in glucose and lipid metabolism and its derangements when the GH/insulin/IGF-1 axis balance fails is well documented
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