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3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and DMSO were purchased from MedChemExpress

Therefore, a functional signal peptide is essential for PLA2G2F

K., Srivastava, A., & Sarkar, A

SCD patients have aberrant metabolic regulation of fumarate, glutamate, glycine, malate, and other metabolites involved in glycolysis, nucleotide catabolism, and glutathione metabolism 3,4,5,6

Similarly to the loss of plasminogen, the loss of enzymatic activity of plasmin had similar findings of reduced fibrin endocytosis by leukocytes, further demonstrating the need for plasmin cleavage of fibrin prior to cellular uptake