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For instance, doxorubicin, a topoisomerase inhibitor, induces DNA damage in cancer cells by interfering with topoisomerases and unwinding supercoiled DNA 24

The mechanism involves complementary pathways

A) mice administered Dihexa through a cannula, B) mice administered Dihexa via intraperitoneal injection, and C) mice administered Dihexa via oral delivery methods 2) In order to determine whether AngIV is involved in the development of Alzheimers, the research team of Sun et al detected the baseline levels of AngIV in both wild type and APP/PS1 mice