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As part of the glutamate-glutamine cycle, astrocytes and oligodendrocytes take up the neurotransmitter glutamate released from neurons at synapses, metabolize it to glutamine using GLUL, and then export it back to neurons, where glutamine is converted back to glutamate using glutaminase (GLS)

Its generally advised to alternate retinol and copper peptides to avoid reduced efficacy or irritation

S., Aepfelbacher, J., Buckless, C., Tsao, A., Kellogg, A., Branch, K., Lee, H., Liu, C

doi: 10.1038/s41467-018-04366-7 129 SiskaPJJiaoJMatosCSingerKDettmerKOefnerPJet al

Interestingly, the glucose levels gradually returned to the baseline by (around) 180 min