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Cortical neurons from G2019S- LRRK2 mice are more vulnerable to stress injury, and exposure to subtoxic doses of MPTP can cause severe motor dysfunction, selective loss of DA neurons, and increased astrocyte activation [101]

Lactoferrin (LF)-conjugated linoleic acid (CLA) micelles, fabricated via carbodiimide coupling and loaded with CLA, demonstrated enhanced in vivo biorelease in brain tissue while improving cognitive function in an aluminum chloride-induced AD animal model [55]

Sulfur rich foods (garlic, onions, cruciferous vegetables), high quality protein (eggs, grass fed meat, whey), selenium sources (Brazil nuts, sardines), and colorful produce rich in vitamin C all support natural glutathione synthesis

Folate concentrations increased in tubers stored in the cold

Calcium D-pantothenate, the calcium salt of pantothenic acid, is also available as a supplement (41)