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42%), enabling immunotherapy selection (e.g., anti-TIM-3 responders) [141]

Moreover, intestinal endoscopic studies, particularly in patients with inflammatory bowel disease (IBD), have shown a SARS-CoV-2 presence in the gut epithelium or stools even after 6 months post-infection, suggestive of a potential viral reservoir triggering sustained inflammatory responses in some cases of LC [180,182,231]

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