Similarly, earlier studies led by Sikiric and colleagues in the 1990s suggested safety and benefit in gastrointestinal conditions such as ulcerative colitis, but these reports were published only in abstracts or local conference proceedings, with no independent replication or peer-reviewed validation
Figure 1bd shows the transmission electron microscopy (TEM) images of spherical particles of N-CDs-DIW (average size 2.4 nm), N-CDs-ET (4.5 nm), and N-CDs-IPA (5.0 nm), respectively
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Despite extensive animal data suggesting efficacy across depression, anxiety, cognitive decline, and ADHD-relevant models, not a single human clinical trial exists for any mental health application