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Method Search strategy To find relevant publications earlier than April 2020, two independent investigators performed a literature search in PubMed, SCOPUS, Embase, ProQuest, and Google Scholar electronic databases using following keywords: glutamine OR Lglutamine OR glutamine supplementation OR glutamine dipeptides AND diabetes mellitus or Type 2 diabetes or type II diabetes or Type 1 diabetes or type I diabetes or diabetic or T2DM or T1DM or noninsulin-dependent diabetes mellitus or insulin-dependent diabetes mellitus or NIDDM or IDDM or hyperglycemia or diabetic or FBS or fasting blood sugar or glycemic outcomes orfasting blood glucose or HOMA-IR or B-cell function or insulin or glucose or glycemic or hyperglycemic

It is a condition where certain body parts are numb or have reduced sensitivity, making it difficult to feel touch, temperature, or pain

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