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[DOI] [PubMed] [Google Scholar] 47.Davari P, Maibach HI

These petroglyphs were created by eroding the stone to form the outlines, rather than using paint

Glutathione is a nucleophilic scavenger and an electron donor

Inhibition of the Xc-system determines the decrease in GSH levels, which indirectly leads to the inactivation of GPX4 and the onset of ferroptosis ( 3+ enters cells with the assistance of transferrin and subsequently converts to Fe 2+ ( 2+ can catalyze the generation of metabolically toxic reactive oxygen species and phospholipid peroxide through the Fenton reaction, leading to cell damage or death (Figure 4)

J.JohnstonA.et al (2020)