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Front Physiol (2020) 11:694

Interestingly, GliT activity was not enhanced in the presence of thioredoxin from Spirulina sp., in activity assays, which indicates that GliT is specific for gliotoxin reduction and that it may operate independently of cellular thioredoxin reductase/thioredoxin systems

RNA activation is a gene regulation phenomenon mediated by a small dsRNA called saRNA, which targets gene promoter sequences to enhance the transcription of the target gene

Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron