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ROS activity in the vessel wall contributes to the formation of oxidized LDL, a major contributor to the pathogenesis of atherosclerosis (205, 206)

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Laboratory studies investigate how senescent microglia and astrocytes contribute to neuroinflammation and disease progression in neurodegenerative disease models, while FOXO4-DRI provides researchers with tools for testing whether senescent cell elimination can restore brain function and reduce neuroinflammatory markers