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In some countries hydroxocobalamin has completely replaced cyanocobalamin as first choice for vitamin B 12 therapy because it is retained in the body longer and can be administered at intervals of up to three months

Although a Statistics Canada population survey published in 2013 found, on average, seniors had only slightly lower levels of B12 than younger adults

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doi: 10.2337/diab.46.12.1939

Both have been well researched and have proven to be very effective, but still demonstrate significant differences: Hydroxocoblamin vs Cyanocobalamin In our opinion, hydroxocobalamin clearly has the advantage over cyanocobalamin