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doi: 10.1146/annurev.physiol.010908.163145

If you are constantly staying up late without trying, or feel extremely tired in the morning, you might be experiencing delayed sleep phase syndrome (DSPS) which disrupts your natural sleep-wake cycle

Selenium potentiates the anticancer effect of cisplatin against oxidative stress and calcium ion signaling-induced intracellular toxicity in MCF-7 breast cancer cells: involvement of the TRPV1 channel

Others dont notice a difference unless they forget to take their shot after 7 days, or they feel the effects wear off after 3-5 days

However, theres no scientific support for this use