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This paper originates from the author team's interest in the question: what has planning theory research focused on in recent years

As previously discussed, neurodegenerative and autoimmune disorders such as AD, MS, and PD are associated with reduced GSH concentrations in the brain making supplemental GSH an attractive therapy if the limitations in delivery can be overcome (Smeyne and Smeyne, 2013)

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However, despite its broad substrate specificity, OCTN1 has relatively low transport efficiency for carnitine and plays a limited role in carnitine transport [168, 169]