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in the other outcome, the injured tissue continues to deteriorate, and the mechanism of the persisting damage involves gliosis with the loss of support of neurotrophic factors, persistent inflammatory receptor activation, and changes in microglia and astrocytes that continue to release harmful cytokines, which promote neuronal death and axonal injury

A10: If hives continue or are accompanied by severe symptoms such as trouble breathing, it is crucial to seek medical attention

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Biochimica et Biophysica Acta, Molecular Basis of Disease

doi: 10.3390/biomedicines10123221