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These findings suggest that high GSH intake is a significant predictor of recurrence and metastasis in breast cancer patients after chemotherapy

Glutaredoxin (Grx), a GSH-dependent disulfide oxidoreductase, catalyzes dithiol reactions, reducing GSH-protein mixed disulfides in a coupled system with GR and NADPH as an electron donor (58, 72)

125 MonteroJ.MariM.ColellA.MoralesA.BasanezG.Garcia-RuizC.et al (2010)

74, 75, 76, 77 The underlying mechanism of increased eNOS expression likely involves increased endothelial production of hydrogen peroxide, which has been shown to increase the expression of eNOS at the transcriptional and translational level

They were first identified in 1997 by Asahara et al