N-acetylcysteine as add-on to antidepressant medication in therapy refractory major depressive disorder patients with increased inflammatory activity: study protocol of a double-blind randomized placebo-controlled trial
High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis
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Thus, various tumors, including glioma, secondary glioblastoma, and acute myeloid leukemia (AML), harboring heterozygous point mutations in the active sites of IDH1/2 show dramatic increases in the R-2-HG levels 111,113,114,115
In those who require acetylcysteine, 2 hours before completion of infusion check ALT/AST and paracetamol concentration (in those with high initial paracetamol concentrations greater than double the 150mg at 4 h nomogram line) to determine need for ongoing acetylcysteine