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Mechanistic summaries on this page are provided for laboratory reference and should be interpreted within controlled experimental settings only. In preclinical models, AOD-9604 has demonstrated significant effects on body composition and adipose tissue metabolism

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Experimental data suggest a possible reduction in apoptotic signaling proteins and an increase in survival-related markers, hinting at a protective or growth-supportive role in cultured cells

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However, in patients treated with diclofenac and glucocorticoids, the risk of peptic ulcer and gastrointestinal bleeding may increase, so special attention should be given in case of prolonged treatment, even in the absence of serious gastrointestinal symptoms