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Compound 13 significantly inhibited the signal transduction pathway mediated by NF-B in LPS-stimulated murine RAW264.7 macrophages, reducing the expression of pro-inflammatory TNF-, COX-2, IL-1, and IL-6, while also decreasing ROS and NO generation

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Conversely, CPP-CAND targets FOXO4, which is explicitly expressed in senescent cells, providing a senescent cell-specific target

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Yet despite getting glowing reviews on social media, most peptides have limited clinical evidence to support health benefits, whether it's helping to heal a rotator cuff injury, improving libido or building muscles