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Vitamin C and some supplements may interfere with certain laboratory tests depending on timing and assay method
Reported side effects are generally mild and include temporary gastrointestinal discomfort, headaches during initial use, occasional fatigue as the body adjusts, and rare nausea, especially when taken without food
[updated 2024 Sep 10
Examples of these health conditions include those with a lack of stomach acid, those who have undergone bariatric surgery, anemia caused by the inability to absorb the vitamin, other autoimmune digestive diseases, as well as several medications
A randomized controlled trial in 167 older adults (50 years) found two-year supplementation with vitamin B 12 (10 g/day), along with folic acid (200 g/day), vitamin B6 (10 mg/day), riboflavin (5 mg/day), and vitamin D (10 g/day), had no effect on bone mineral density (total hip, femoral neck, or lumbar spine) compared to the control group only receiving vitamin D (10 g/day ) (116)
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