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In some embodiments, the otic formulation or composition comprises between about 0.001% to about 80% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

However, in the Phase I/II ACTION-Galactosemia study, which focused on adults, treatment with govorestat resulted in a drop in galactitol concentrations, according to Applied Therapeutics

This will require an element of transparency and patient consent

[4] Phase 3 trials (the TRIUMPH programme) are currently underway, with results anticipated in the coming years

As a formally trained board certified physician, he comes at this topic through the lens of a physician, but also somebody who is very interested in the current status and future of peptide medicine