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The fact that both alcohol consumption and tobacco smoking can interact with the sympathetic nervous system could explain a synergistic effect

The long-run series shows persistence: tobacco area was 4.4-4.6 lakh hectares in the late 1960s and early 1970s, touched 5.0-5.1 lakh hectares in the late 1970s and again in 1998-99, dipped sharply to 2.6 lakh hectares in 2000-01, and then returned to a familiar band of around 3.5 to 4.9 lakh hectares for most years since

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