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Investigators also have hypothesized that cyclosporine can modify resistance to chemotherapy by augmenting the cytotoxic effect of drugs through inducing a GSH deficiency

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During this era of research, other groups focused on the molecular machinery responsible for phase II detoxification enzyme gene expression

10.3390/antiox9111103 22 JensenT

These toxins, called mycotoxins, can build up from exposure to moldy environments or contaminated food