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In order to improve outcomes, biphasic scaffolds can be created with a softer upper layer containing chondrogenic factors (e.g., TGF-, chondroitin sulfate) and a stiffer lower layer, often loaded with calcium phosphate, hydroxyapatite, or bone morphogenetic protein (BMP), to provide structural support of the above cartilage layer and to promote osteogenic tissue formation and boney integration

(Source 2) The papaya is a large, pear-shaped fruit with deep orange flesh originating in Central America

Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression

Glutathione is present in every cell of the body, and the depletion of glutathione is noted in a wide range of medical conditions