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Proceedings of the National Academy of Sciences of the United States of America, 73 (7), 24092413

VY prepared the original draft

Menten AI in Toronto applies machine-learning-guided protein design to create peptides with desired pharmacological properties, leveraging structure-based modeling for binding affinity and metabolic stability

Key Takeaways TB-500 is a synthetic fragment of Thymosin Beta-4: It isolates the active repair sequence of a naturally occurring protein found in virtually every human cell, concentrating the tissue repair and anti-inflammatory signaling without manufacturing the full protein

doi: 10.4103/ijo.IJO_721_20 288 PeelerCEGonzalezE