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This profile enables a cigarette to be completely smoked in 10 puffs and an IQOS stick to be finished in 12 inhalations

Prolonged exposure can increase the risk of long-term respiratory issues like recurring bronchitis and chronic obstructive pulmonary disease (COPD)

Further, there may be differential immune responses of upper versus lower airways to e-cigarette exposures that can vary with past inhalant use (Figure 7)

According to critics of the tobacco industry, the holes create a flexible dosing system that allows addicted smokers to maintain the tar and nicotine levels they crave while believing they are receiving lower, safer doses

You want resistance, not blockage